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In animal studies, AOD-9604 reduced body weight gain by over 50% in obese mice during a 19-day treatment period, and significantly increased fat oxidation all without affecting insulin sensitivity or glucose regulation.[1,3] A randomized controlled trial in humans found that participants taking 1 mg of AOD-9604 daily lost an average of 2.8 kg (~6 lbs) over 23 weeks, compared to 0.8 kg (~1.7 lbs) in the placebo group

Underlying health conditions can also lead to low B12 levels

The only side effect Ive experienced is a bit of constipation, but I manage that easily with over-the-counter senna

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What Happens When Your B12 Is Low

"The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese subjects and beta(3)-AR knock-out subjects." Endocrinology