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However, the elimination of publication bias using trim and fill analysis revealed that NAC also could decrease E2 levels and endometrial thickness

Additionally, the modulation of cystine-glutamate exchange via the system x c has been suggested as a new strategy to diminish the excitatory glutamatergic transmission observed after drugs of abuse, while drugs that influence that systemsuch as N-acetylcysteine (NAC)were considered as promising targets for the development of novel pharmacotherapies of SUD

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As a result, a hypertonic solution obtained by adding 100 mOsm.l 1 of mannitol to isotonic PBS medium (Mannitol, osmolarity increased to ~400 mOsm.l 1 without modification of ion concentrations) greatly decreased MSU and CPP crystal-induced IL-1 production (200 g/ml, 3 h, Fig

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The pre- and post-treatment subscores in five different domains are outlined in Table 4