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Thus, purposeful fluid intake has a substantial behavioral component that interacts with physiological mechanisms

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Elevated homocysteine levels (which rise when vitamin B12, folic acid, or vitamin B6 are low) have also been associated in observational studies with higher rates of Alzheimers disease and dementia

In nonresponsive cases, doctors can consider using parenteral B12, especially if oral B12 treatment has been used in the past or when serum vitamin B12 is not normalized (Table 2)

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