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SKU: 98492836112
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Combined treatment reduced tumor burden in vivo , suggesting HMGB1-mediated ferroptosis sensitizes tumors to NK clearance ( 4 -treated cells, marked by reduced SLC7A11, GPX4, ferritin, and increased MDA, CD71, transferrin, and HMGB1

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This view was further supported by the impaired suppression of the -H2AX foci in the DsupC-expressing cells (Supplementary Fig

A groundbreaking approach introduced by Guo, Boda et al., outlines a novel cancer therapy tactic that involves the creation of a ROS-sensitive polymer, PHPM, which is utilized to concurrently encapsulate elesclomol and copper into nanoparticles, dubbed NP@ESCu