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Moreover, identifying mutational signatures may inform therapeutic decisions, as tumors with specific exposure-driven mutations can exhibit distinct treatment responses [130]

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Dehydration Causes: Not drinking enough water Excessive sweating, such as during intense physical activity or hot weather Vomiting and diarrhea Fever Certain medications Diabetes Alcohol consumption Infections Kidney problems Aging (older adults are more prone to dehydration) Signs of Dehydration Intense thirst Disorientation or confusion Feeling lightheaded or dizzy Extreme tiredness or fatigue Urine that is darker in color Reduced frequency of urination or diminished urge to urinate Sunken-looking eyes Skin lacking elasticity Faster heartbeat and breathing Decreased blood pressure Mental confusion or delirium What are IV Fluids