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Tumors can also hijack DC maturation to decrease MHC expression and destroy the costimulatory machinery by secreting suppressive factors such as TGF-, interleukin-10 (IL-10), and vascular endothelial growth factor (VEGF) [110]

Although vitamin C is a vitamin that the body needs, it cannot be produced in the body

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doi: 10.1007/s00018-013-1539-2

Additionally, it would be valuable to investigate whether restoring iron homeostasis in CD11c + myeloid cellssuch as through iron chelator administration or inhibition of key components of iron metabolism, including IRP2can resolve inflammation and promote tissue repair

Crosby P, Hamnett R, Putker M, Hoyle NP, Reed M, Karam CJ, Maywood ES, Stangherlin A, Chesham JE, Hayter EA, Rosenbrier-Ribeiro L, Newham P, Clevers H, Bechtold DA, ONeill JS (2019) Insulin/IGF-1 drives PERIOD synthesis to entrain circadian rhythms with feeding time