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And the iron deposits observed in the cerebral cortex and hippocampus of AD patients are consistent with the distribution and location of A plaques (94, 97)

Mitochondrial dynamics Changes in mitochondrial morphology are mediated by mitochondrial dynamic markers that regulate processes such as mitophagy, fusion, and fission

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Indeed, the first oncogene identified (SRC) was also the first Tyr kinase to be discovered 11,12 , and over 50 Tyr kinase inhibitorsincluding Gleevec, one of the earliest successful molecular medicinesare now FDA-approved cancer therapies 13,14

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Together with opsonins, these antibodies facilitate the recognition of senescent RBCs by phagocytic cells, leading to their clearance predominantly in the spleen and liver as part of the reticuloendothelial system