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1833-A IDENTIFYING THE POPULATION AT RISK OF HCC IN NON-ACLD CHRONIC HEPATITIS C PATIENTS CURED BY DIRECT-ACTING AGENTS: A STRATEGIC APPROACH Yen-Chun Liu 1,2 , Ya-Ting Cheng 1,2 , Yi-Cheng Chen 1,2 , Rachel Wen-Juei Jeng 1,2 , Chun-Yen Lin 1,2 , Rong-Nan Chien 1,2 , Dar-In Tai 1,2 , I-Shyan Sheen 1,2 and Yi-Chung Hsieh 1,2 , (1)Chang Gung Memorial Hospital, Linkou Branch, Taiwan, (2)College of Medicine, Chang Gung University, Taiwan Background: HCC surveillance is recommended for chronic hepatitis C (CHC) patients with advanced fibrosis (F3) or cirrhosis (F4) after successful viral eradication, according to clinical guidelines

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With aging, reduced cellular metabolic activity leads to the accumulation of ROS, resulting in abnormal protein aggregation and organelle damage, which ultimately cause UPS dysfunction and impaired autophagy

FendlBWeissREichhornTLinsbergerIAfonyushkinTPuhmFet alExtracellular vesicles are associated with Creactive protein in sepsis