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TB-500 may bind to globular actin (G-actin) and modulate the assembly of actin filaments

Shapiro-Wilk test revealed the differences were normally distributed, so a paired t-test was used for further statistical analysis

In the present study, the activation of JNK, ERK1/2 and p38 signals was significantly increased in the EpCAM +/ + DSS group but not in the WT + DSS group, and importantly the activation of JNK and ERK1/2 was also higher in EpCAM +/ mice than WT mice (Figure 2C)

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