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Free radicals are unstable atoms that can damage cells, leading to what scientists call oxidative stress

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Garcia-Manero G, Montalban-Bravo G, Sasaki K, Daver NG, Jabbour EJ, Alvarado Y, DiNardo CD, Ravandi F, Borthakur G , Bose P, Pemmaraju N, Naqvi K, Cortes JE, Kadia TM, Konopleva MY, Rausch CR, Gasior Y, Kantarjian H

Keywords: HIF-1, Immunologic cell death, Radiotherapy, Chemotherapy, Radiosensitivity, Chemosensitivity, Anti-tumor immunity, Immunosuppression Introduction Radiotherapy and chemotherapy are two of the most commonly used treatment modalities for malignant cancers