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Furthermore, Gclc -deficient FoB have a block in the mitochondrial electron transport chain (ETC) due to diminished complex I and II activity and thereby accumulate the tricarboxylic acid cycle metabolite succinate

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(DOCX) S2 Fig

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Protection by intracellular acidosis against the onset of cell death

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Surprisingly, we still detected an induction effect of DMF on most of the factors studied despite NRF2 silencing (Fig

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narrows pores and improves skin color

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