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Ms all de 14 das puede producirse prdida progresiva de coordinacin del cobre y degradacin peptdica

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doi: 10.1097/CM9.0000000000003189 61 YangYWangYGuoLGaoWTangTLYanM

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This "paradoxical response" (where treatment temporarily makes symptoms worse) includes: Numbness and tingling Shooting pains Joint pain Increased sensitivity Temporary inflammation (swelling and irritation) While these symptoms generally indicate that treatment is working (as nerves begin to repair themselves), they can be distressing for patients and may require additional treatment for comfort

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