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Neural cell migration is also activated by stromal cell-derived factor 1/chemokine receptor 4 (SDF-1/CXCR4) [88, 89] and neuronal cells express CXCR4, the cognate receptor for SDF-1

Proving this principle, an eed1 -deletion mutant, which reverts to yeast growth after inducing germination, displayed avirulence in in vitro infection models 8

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doi: 10.3389/fphar.2025.1687805 Received 18 August 2025 Revised 11 November 2025 Accepted 15 December 2025 Published 22 January 2026 Volume 16 - 2025 Edited by Nicole James, Women & Infants Hospital of Rhode Island, United States Reviewed by Nazia Nazam, Aligarh Muslim University, India Salman Ahmed, University of Karachi, Pakistan Updates Copyright 2026 Muttiah and Abdullah