glutathione signaling pathways - an overview Apoptosis and glutathione: beyond an

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and (3) RNA integrity was assessed using the RNA Nano 6000 Assay Kit of the Bioanalyzer 2100 system (Agilent Technologies, CA, USA)

Jagannathan, S

However, as mRNA levels do not necessarily reflect protein abundance or enzymatic activity, these findings should be interpreted cautiously and verified in future studies at the protein or functional level

Implicated mechanisms include upregulation of molecular pathways involved in oxidative stress, aberrant calcium signaling, silencing of transcription factors and histone deacetylases, and deregulation of cytoskeleton-associated proteins