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After 24 h incubation, the culture medium was collected and centrifuged for 10 min at 12 000 rpm

LTF, like many other human milk proteins, clearly contains multiple entry points for interaction with innate receptors that mediate downstream activities related to danger signals (55)

AFB1 is well-known for its carcinogenic effects, and it is classified in group I of the human carcinogenic compounds ( Poultry farming is one of the most important segments of agro-industries and it can be at a high risk of negative effects in case of AFB1 feed contamination, which could result in low performance and decreased quality of both eggs and meat, with negative economic feedback ( In vivo studies performed in both laboratory and farm species have demonstrated the capability of AFB1 to induce oxidative stress in several organs and tissues, including the kidney ( Curcumin (CURC), a polyphenolic compound which belongs to the curcuminoid group, has several pharmacological effects, including anti-inflammatory, antioxidant, radioprotective, and tissue protective activity in both experimental animals and humans ( In the present work, we investigated the benefits of the dietary supplementation with CURC from turmeric powder in broilers exposed to AFB1 at concentrations approaching the EU maximum permitted limits

Linjawi, S

J Clin Endocrinol Metab 89 : 667674 Swearingen B et al

Trends in Cancer