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Macrophage cytokines: Involvement in immunity and infectious diseases

Here we report the engineering and preclinical development of a bimodal molecule that integrates NMDA receptor antagonism with glucagon-like peptide-1 (GLP-1) receptor agonism to effectively reverse obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease

Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion

Diagnosing Hair Loss Effective treatment for hair loss begins with identifying the underlying cause

Inhibiting the activity of system Xc- affects the synthesis of GSH by inhibiting the absorption of cystine, which leads to a decrease in GPX activity, a decrease in cell antioxidant capacity, accumulation of lipid ROS, and ultimately the occurrence of oxidative damage and ferroptosis

Dos Santos AC, Frana TCS, Venzon L, Polli V, Polleti G, Trembulak E, Mendes-Pilati SF, Mota da Silva L (2024) Are silymarin and N-acetylcysteine able to prevent liver damage mediated by multiple factors