glutathione protein folding ER stress, misfolding, and oxidative stress are intimately Redox Regulation by Protein S-Glutathionylation:

Redox Regulation by Protein S Glutathionylation: From Molecular Mechanisms to Implications in Health and Disease The antioxidant glutathione plays a key role in protein folding The team discovered a few years ago that if glutathione levels aren't precisely maintained in mitochondria, all systems fail. On the heels genes involved in glutathione metabolism Differentially Expressed Regulating Metabolism, Protein Folding, and Unfolded Protein Response Pancreatic Cells in Type 2 Diabetes Mellitus Transcriptome and physiological analysis revealed Glutaredoxin catalysis requires two distinct glutathione interaction sites Nature Communications Powerful Antioxidant Found To Play a Key Role in Proper Protein Folding Acceleration of disulfidecoupled protein folding using glutathione derivatives Okumura 2011 The FEBS Journal Wiley Online Library

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