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Trimetazidine (10 or 20 mg/kg/day for up to 5 weeks) also significantly alleviated pentylenetetrazole-induced seizure in mice while reducing lipid peroxidation and increasing glutathione levels in the brain [176]

Mechanistic investigations revealed that LCA upregulates the production of several components of flagella, which are essential for LCA-induced biofilm formation and form part of the biofilm matrix