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doi:10.1056/NEJMoa2301972 PubMed: This landmark study demonstrated 24.2% mean weight loss at 48 weeks with the 12mg dose in 338 adults with obesity, establishing retatrutide as the most effective obesity medication tested to date

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It is noteworthy that the volunteers included in this study had mild COVID-19 in 2021, prior to the emergence of the SARS-CoV-2 Omicron variant and when the Brazilian population had not completed the full COVID-19 vaccination schedule