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As illustrated in this picture, PDEGF and FGF2 also lead to activation of the Ras/MAPK pathways and therefore proliferation and on activation of migration

2025 Sep;24(9):e70162

Even with regulations, a significant imbalance would not be sustainable for the industry in the long term

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The underlying tissue is undergoing active remodeling

Consistent with this finding, we observed higher expression of TGF and p-Smad2 in NP and L929 cocultures, but no expression of either was observed in NP and 293T cocultures (Supplementary Fig