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[159] pretreated BMSCs with a low concentration HO, which activated the Nrf2 pathway by relieving Keap1-mediated inhibition of Nrf2, promoted its nuclear translocation, and initiated the expression of antioxidant enzyme genes (e.g., SOD, CAT)

Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization

Zahreddine H, Borden KLB

Drought and salt stress tolerance of an Arabidopsis glutathione S -transferase U17 knockout mutant are attributed to the combined effect of glutathione and abscisic acid

In conclusion, gaining an understanding of the intricacies of 1C metabolism has the potential to pave the way for possibilities in developing therapies and approaches to minimize the effects of these diseases on human well-being