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The failure of mitochondrial steroidogenesis in GCs can result in aberrant oocyte development, especially when estrogen levels in follicular fluid are low and progesterone levels are high, affecting proper meiosis and late cleavage of oocytes (80, 102, 103)

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214 ARF6 negatively regulates ACSL4 expression and regulates gemcitabine resistance by influencing the sensitivity of pancreatic cancer cells to oxidative stress and ferroptosis