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In addition to gastrointestinal hormones, butyrate also has positive effects on the secretion and metabolic actions of growth hormone (GH) (102), which is a type of somatotropin hormone secreted from the pituitary gland in a pulsatile manner (87)

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Reported laboratory observations include activation of downstream PI3K/Akt and MAPK/ERK signaling cascades and associated effects on cell proliferation, protein-synthesis pathways, and anti-apoptotic signaling in cultured cells