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Lower Extremity Malignancies Masquerading as Ulcers Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) Nursing.56An ulcer is a local defect or excavation of the skin or mucous membrane, caused by tissue necrosis. Key point: Ulcers often fail to heal easily due to ongoing tissue damage. # Oral pigmented lesions: Clinicopathologic features and review of the literature PMC Achromic Melanoma
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