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Consequently the action of a drug may be adversely affected by a micronutrient (e.g

Receptor autophosphorylation, downstream phosphorylation of IRS-1 and Shc, and activation of PI3K and MAPK occur with similar kinetics to native IGF-1 once the ligand reaches the receptor

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Frontiers in Neuroscience, 13

Due to the heterogeneity of the molecules considered and the laboratory methodologies, it was not possible to perform a meta-analysis, and the main results are reported in Table 1