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doi: 10.1006/geno.1994.1655 192 ZhaoLVogtPK

D., Higgins, D

10 lb d

Bredesen: Absolutely

Rats in LLLAE and HLLAE groups were administrated with 0.5 g crude drug/(kg.d) and 3.0 g crude drug/(kg.d) LLAE, respectively, by gavages

This means that more methylfolate is diverted towards thymidine production, and less is available for methylation reactions.31 In particular, low methylfolate levels are associated with low glutathione.32 Glutathione is important for reducing oxidative stress and helping to halt the self-perpetuating peroxynitrite cycle