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[DOI] [PubMed] [Google Scholar] 73.Dal Negro R., Pozzi E., Cella S.G

Swisher SG , Roth JA, Neumanitis J, Lawrence DD, Kemp BL, Carrasco CH, Connors C, El-Nagger AK, Fossela FV, Glisson BS, Hong WK, Khuri FR, Kurie JM, Lee JJ, Lee JS, Merritt JA, Nesbitt JC, Nguyen D, Pisters KMW, Jr PJ, Schrump DS, Shin DM, Perez-Soler R, Walsh GL

Human trials show modest, inconsistent, and non-durable lightening, with effects fading after treatment stops and much of the research being small or industry-linked

To identify cellular proteins that bind m11, we screened cDNA expression libraries from diverse mouse cell lines and tissues with m11Fc, a fusion protein comprising the extracellular domain of m11 (amino acids 1212) fused to a human IgG1 Fc domain, and identified a cDNA encoding mouse CD44, a transmembrane glycoprotein involved in cell adhesion and signalling 12

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Petrovic, S