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This can result in complications such as cardiac hemosiderosis (leading to heart failure), hepatic fibrosis and cirrhosis, diabetes mellitus (due to pancreatic iron deposition), and hypogonadotropic hypogonadism causing delayed or absent puberty

302 However, an upregulation of neutrophil CXCR2 expression was observed during the relapse phase of ocular leukoaraiosis

PMID: 19891010

Cancer is often driven by oxidative DNA damage, and autoimmune diseases can result from chronic oxidative stress-induced inflammation

Phenotypic screening approaches for Chagas disease drug discovery

In contrast, the hydrodynamic size of MnO 2 @CaCO 3 @PEG nanoparticles was 137 nm, which was slightly smaller than that of their corresponding AS-loaded counterparts (Figure 2D)