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The question is: does the scientific research actually back up these anecdotal claims

We observed membrane populations of Rac, RhoA and Rap1 but not Cdc42

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However, we proposed to codify our current cost scoring policy, previously finalized in the CY 2017 QPP final rule (81 FR 77308 through 77311), with modification by adding language at 414.1380(b)(2)(i)(A)