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doi: 10.1111/j.1600-0463.2012.02882.x

This antioxidant has been associated with a delay in the clinical onset of the disease (Table 1) in transgenic mice that express mutant copies of the gene encoding SOD1 (an animal model of ALS) (Gurney et al., 1996)

on the other hand, changes of gut microbial composition during neurodevelopment in early life may be detrimental for the CNS and leads to neurological disorders in later life (Louwies et al., 2019)