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Shenuarin Bhuiyan 2 Gretchen Galliano 8 Bo Wei 9 Lin Tan 9 Iqbal Mahmud 9 Ida Surakka 3 Minerva Garcia-Barrio 3 Philip Lorenzi 9 Eyal Gottlieb 9 Eduardo Salido 10 Jifeng Zhang 3 Wayne Orr 2 Wanqing Liu 11 Monica Diaz-Gavilan 12 Eugene Chen 3 Nirav Dhanesha 2 Paul Thevenot 8 Ari Cohen 8 Arif Yurdagul 2 , 1 LSU Health Shreveport, 2 LSU Health, Shreveport, LA, USA, 3 University of Michigan, Ann Arbor, MI, USA, 4 Ochsner Health, New Orleans, LA, USA, 5 University of Michigan School of Public Health, Ann Arbor, MI 48109, USA, 6 Unidad de Excelencia de Qumica Aplicada a Biomedicina y Medioambiente, Campus Cartuja s/n, Spain, 7 University of Pittsburgh, Pittsburgh, PA, 15261, USA, 8 Ochsner Medical Center - New Orleans, LA, USA, 9 MD Anderson Cancer Center, Houston, TX 77030, 10 Universidad de La Laguna, Tenerife 38320, Spain, 11 Wayne State University, MI, USA, 12 Unidad de Excelencia de Qumica Aplicada a Biomedicina y Medioambiente, Granada, Spain Background: Metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed

Immunological mechanisms of ALD Triggers of the immune response in ALD Enteric dysbiosis The mammalian intestine contains a variety of microbes (bacteria, archaea, fungi, and viruses) and expresses over 3 million genes

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