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First pass metabolism typically results in low bioavailability, resulting in adjusted dosages

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Also in 2005, the mRNA-sequence of the equine psoriasin (a calcium-binding protein of the S100-protein family with antimicrobial activities [38]) was described and the gene was mapped to equine chromosome 5 [39]

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2.2 Health and the power of lifestyle The desire for a happy and long life (with as few years lived with disability as possibleespecially at the end of one's lifespan) has been a fundamental human aspiration and traces back to the beginning of humankind (53)