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Autoimmune Progesterone Dermatitis (APD) also known as progestogen hypersensitivity is a rare immune-mediated reaction in which the body mounts an allergic or autoimmune response to endogenous progesterone or synthetic progestins, leading to cyclical skin and systemic symptoms that worsen during the luteal phase of the menstrual cycle

Mol Neurodegener 7:112

TMA syndromes require rapid intervention with plasmapheresis, immunosuppressive agents (corticosteroids), or complement-inhibiting therapies (e.g., eculizumab) due to their natural pathophysiology of endothelial damage and complement dysregulation

While the chemical-based nature of ion exchange is cheaper and often times more amino acids are captured, a drawback to the ion exchange method is that you may also lose some of the other important compounds in the whey product, such as lactoferrin and many of the immunoglobulins

10.1021/acs.jafc.0c00277 J Agric Food Chem

These findings suggest potential applications in tissue engineering research