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Typically, injections are administered weekly for the first few months, then reduced to bi-weekly or monthly for maintenance

The following plot from the study shows this effect

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These anti-inflammatory actions encompass the regulation of various inflammatory responses such as NF-B activation, T-cell proliferation, adhesion molecule expression, inflammatory cytokine and chemokine receptor expression, and inflammatory cell migration [38]

CPZ is a commonly used compound to model demyelination in mice, producing reproducible demyelination after 6 weeks of treatment (Hiremath et al., 1998)