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GIP stands for glucose-dependent insulinotropic polypeptide, another hormone involved in regulating metabolism

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Hypothyroidism is often a cause of Vitamin B12 deficiency, arising from the reduced absorption of B12, poor utilisation of the liver, and general organ disfunction associated with hypothyroidism, and sometimes by dietary insufficiency of B12 (particularly in the case of a vegetarian diet)

87 Alternatively, hyperexcitable small fiber neurons in PDPN might be more susceptible to bioenergetic failure, increasing distal nerve fiber degeneration