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At 6, 12, 24, and 48 h post-administration, mice were received intraperitoneal injection of D-luciferin potassium salt at 150 mg/kg and euthanized 12 min later

These primary KCs were cultured in flasks in charcoal stripped plasma containing media, treated with E2 (1 nM 6 h) followed by stimulation with LPS (1 g/mL, 4 h)