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Antiga et al

Moreover, matrix metalloproteinases (MMP) 2 and MMP9, effector factors secreted by microglia, exhibit enhanced expression under the pathological conditions of dementia, promoting neuroinflammation and accelerating neuronal degeneration (Qiu et al., 2023)

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Mice lacking either TAP-1 (transporter associated with antigen processing 1) or 2 microglobulin, crucial components for MHC-I antigen presentation, display impaired CD8 + T cell responses and succumb more rapidly post- M

Global, regional, and national burden of Alzheimers disease and other dementias, 1990-2019

Globally, an estimated 500 to 600 million peopleabout 7% of the populationare affected