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Preclinical studies have evaluated KD primarily in SOD1 transgenic mouse models, which exhibit progressive motor neuron degeneration, muscle weakness, and mitochondrial dysfunction, thereby recapitulating key features of disease progression [40, 102]

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CNS and Neurological Disorders-Drug Targets, 17 (8), 590594

The negative results of the latter study may, at least partly, be due to the large heterogeneity of causes of AKI (trauma, hypertension, surgery, drugs or sepsis) and/or the delayed initiation of rhIGF-1 treatment, i.e., after established AKI

Furthermore, findings of aberrant intra-network homogeneity involving the DMN of bipolar patients, was also reproduced (94)

L-Glutamine vs