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It's produced in the body from the three amino acids cysteine, glutamic acid, and glycine

doi: 10.1016/j.apsb.2015.05.005 334 ChenRYShiJJLiuYJYuJLiCYTaoFet al

doi: 10.1016/j.atherosclerosis.2016.08.019 103 SunJLundstromSLZhangBZubarevRASteuerJGillgrenPet al

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As recently as March 2018, it was reported in the International Journal of Sports Nutrition and Exercise Metabolism that, It is likely that the lack of efficacy in many studies is due to its low bioavailability and failure to increase muscle L-carnitine stores. References: Gnoni A, Longo S, Gnoni GV, Giudetti AM

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