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Consequently, NRF2 activity increases, leading to the elevated expression of antioxidant enzymes such as glutathione S-transferase, NAD(P)H quinone oxidoreductase 1, and heme oxygenase-1 (260)

Many Asian and African countries also restrict its concentration or require prescriptions

The gut microbiome and its impact on the brain

Stridh H, Kimland M, Jones DP, Orrenius S, Hampton BM (1998) Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis

Gut microbiome in health and disease

Steroids, especially when taken in high doses (supraphysiologic) or for a long time, can lead to a variety of side effects, some of which can be serious and long-lasting