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For interventions, stage-specific combination therapies should be designed for the 672-h secondary-injury window

Dysfunction of the mitochondrial electron transport chain may contribute to late multi-organ complications in PA and MMA [25], including the formation of megamitochondria in kidney proximal tubules, seen in MMA patients with chronic kidney disease [38]

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Sun damage, especially a history of peeling sunburns, is the main risk factor for melanoma

It is important to screen at an early age or as soon as possible as there may be corrective measures available

the liver, spleen, and kidneys