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The hydroxyl groups on the terminal rings can also form mono- or diester derivatives with fatty acids, which are the predominant forms in many natural sources and further contribute to the diversity of astaxanthin compounds observed in biological systems ( Substantial evidence indicates that AST can downregulate microglial activation and reduce the production of cytotoxic factors

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Following this concussive-like brain injury, the decrease in NR2A expression in the younger brain is thought to contribute to the failure to show EE plasticity acutely (Giza et al., 2006)

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