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The table below organizes what the literature actually shows, with the evidence tier stated explicitly (clinical human data, preclinical lab/animal data, or anecdotal/inferred)

Dehydration exacerbates nausea, causes headaches (often misattributed to the peptide itself), and can lead to dizziness and lightheadedness

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a mild stinging sensation may occur due to the quinolinium structure

Anxiety and stress-related disorders DSIPs calming presence may extend a helping hand to those grappling with the clutches of anxiety and stress

& Tomy, C