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Mechanisms of overcoming intrinsic resistance to gemcitabine in pancreatic ductal adenocarcinoma through the redox modulation

J Cutan Pathol 47(10):954-959, 2020

Mechanistically, AC increases toll-like receptor 4 (TLR4) expression, activates the myeloid differentiation primary response 88 (MyD88) axis, and reduces NF-B mRNA levels, but shows no toxic effects on normal cells (Daneshforouz et al

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These therapeutic effects were evidenced by improved Forced Expiratory Volume in one second (FEV1) and Peak Expiratory Flow (PEF) values and symptoms scores, reduced inhaled 2-agonist usage, number of peripheral eosinophils, and serum IL-5, IL-13, and IgE, with increased serum cortisol and IFN- (Fig

BPC-157 enhances the activity of natural growth factors in the body that promote healing