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Chatterjee S, Dhar S, Sengupta B, Ghosh A, De M, Roy S, et al

136 , jcs260685 (2023)

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A2E intracellular accumulation enhances RPE photosensitization, generating high levels of both hydrogen peroxide (H 2 O 2 ) and superoxide anion (O 2 ) when the cells are exposed to blue-violet light, providing a possible cellular mechanism to explain the RPE dysfunction that causes AMD [5]