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All authors revised and approved the final manuscript

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3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) viability assay The PC-12 cells were seeded onto a 96-well plate at a density of 1 10 5 cells per well and incubated for 24 h at 37 2 C in a 5% CO 2 -humidified incubator

Avoid using tirzepatide with other GLP-1 receptor agonists

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6 se observa dos tipos de respuesta de insulina frente a una infusin de glucosa de 50 a 300 mg/dL: la respuesta rpida seguida de la respuesta lenta, que ocurre mientras se mantiene la concentracin alta de glucosa