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Another concern about vitamins and their involvement in the pathogenesis of asthma is the problem of deficiencies, which can be related to malnutrition, lifestyle, or place of residence

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Adverse Reactions/Side Effects The following clinically significant adverse reactions are described elsewhere in the labeling: Neutropenia [see Warnings and Precautions (5.1)] ILD/Pneumonitis [see Warnings and Precautions (5.2)] 6.1 Clinical Studies Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

nhtsa.gov Total body water and mild dehydrations effect on plasma volume counterpoint research on short-term fluid restriction.