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Furthermore, the in vivo fate of assembled nanostructures and potential immunogenicity from peptide or nucleic acid-based modules warrant careful consideration [270,271,272,273,274]

Ammoniaand its associated nitrogenis a toxic byproduct that requires activation of the urea cycle for homeostasis and prevention of ammonia toxicity

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However, this approach frequently fails to address the underlying "hardware" failurethe cellular and subcellular pathology resulting from the neurometabolic cascade of injury

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