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Inject subcutaneously into fatty tissue, typically the abdomen for better absorption

In an EMs mouse model, CHS-Iva was administered at 50 mg/kg

Given caffeine is known to have antioxidant and anti-inflammatory properties as discussed in previous text, it may have mitigated oxidative stress-related anxiety in this model

Qu SY, Li XY, Heng X, Qi YY, Ge PY, Ni SJ, Yao ZY, Guo R, Yang NY, Cao Y, Zhang QC, Zhu HX (2021) Analysis of antidepressant activity of Huang-lian Jie-du decoction through network pharmacology and metabolomics

References: Saccharomyces cerevisiae and its industrial applications

These findings provide a novel perspective and potential targets for elucidating its pathophysiological mechanisms and developing innovative diagnostic and therapeutic strategies (103, 105)