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The use of animal models of human disease in research and drug testing should meet three criteria: construct validity, face validity and predictive validity (Nestler and Hyman, 2010)

This process leads to increased free Fe 2+ in cells and increased ferritin, manifested by iron deposition in the brain

In NMO the myelin deteriorates mostly in the optic nerve, which can lead to blindness, and in the spinal cord

In contrast, the role of mTORC2 in aging remains less defined, with studies showing that reduced mTORC2 activity shortens lifespan in mice (Nojima et al., 2013

8 CoEnzyme Q10 (10,000 mg) Improves skin texture , reduces wrinkles , and boosts skin repair